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By, The University of Texas at Austin College of Pharmacy

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You may have seen both Viagra and Cialis on the market but have also seen some generic medications appear to be more popular among consumers. This article discusses selected medications available on the market, their dosages, potential side effects, and current state regulations. We also provide tips for keeping a current and updated on medications available on the market.

Tadalafil

This drug is similar to Cialis but has the same active ingredient and uses. Tadalafil is used to treat erectile dysfunction (ED), or inability to get or maintain an erection during sexual activity. It is also used for the treatment of pulmonary arterial hypertension (PAH).

Tadalafil may also be used for purposes not listed in this medication guide.

Sildenafil (Viagra)

This drug is similar to Viagra but has the same active ingredient and uses. Sildenafil is used to treat erectile dysfunction (ED).

Sildenafil may also be used for purposes not listed in this medication guide.

Cialis (Tadalafil)

This drug is similar to Tadalafil but has the same active ingredient and uses. Tadalafil is used to treat erectile dysfunction (ED).

Sildenafil (Viagra Connect)

How to Use Tadalafil

Take this medication exactly as prescribed by your doctor. Follow these directions to get the most out of it:

  • Take one tablet with water.
  • Swallow one tablet whole with water.
  • Do not take more than one tablet within a 24-hour period.

If you have any questions regarding your medication, talk to your doctor or pharmacist.

How Long Does Tadalafil Last

Tadalafil is a PDE5 inhibitor that allows for the relaxation of smooth muscle in the penis. This allows for increased blood flow and helps get and maintain an erection. It can take several daily doses to cause an erection but can still cause side effects such as headache, nausea, and facial flushing.

Tadalafil can be taken with or without food. If you take it with a heavy meal, it may reduce the effectiveness of this medication. If you take it with food, you may experience some or all of the following effects:

  • Frequent dosing can increase the risk of side effects.
  • It does not protect against sexually transmitted diseases.
  • It may lead to sunburns or allergic reactions.

Lamisil (Lamisil)

1-20 mg once daily; 2-8 mg once daily; 5-20 mg orally once daily. For the treatment of erectile dysfunction; see also section 6.8.

Treatment of erectile dysfunction (ED):

Treatment of erectile dysfunction (impotence):

  • Treatment of impotence (impotence) as determined by the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. See sections 6.8, 8.2, 8.3, 8.4, 8.5, 8.6, 8.8, 8.9, 10.1, 10.2, 10.3, 10.4, 10.8, 11.8, 12.1, 12.2, 13.2, 13.4, 13.5, 14.4, 14.5, 15.1, 15.2, 15.4, 16.1, 16.2, 17.1, 17.2, 18.1, 18.2, 20.1, 20.2, 20.3, 21.1, 21.2, 21.3, 21.4, 21.5, 21.6, 21.7, 21.8, 22.1, and 21.9.
  • Treatment of impotence as determined by the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. See section 6.8.
  • Treatment of erectile dysfunction (ED)

Sildenafil (Viagra)

1-100 mg; 5 mg; 10 mg orally once daily; 20 mg orally once daily

  • See also section 6.8.
  • Treatment of erectile dysfunction (impotence)

Phentermine (Benadryl)

1-200 mg; 5 mg; 10 mg orally once daily; 20 mg orally once daily

  • Treatment of erectile dysfunction (impotence) as determined by the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse.

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About Viagra

Viagrais an oral medicine used to treat erectile dysfunction (ED) in men. It contains the active ingredient sildenafil citrate, which is a PDE5 inhibitor. Viagra works by relaxing the muscles in the walls of blood vessels, allowing blood to flow into the penis to achieve or maintain an erection. Viagra can be taken on an empty stomach, especially with antifungal therapy or with food close to when it is most effective. Viagra should not be taken more than once a day. To get the most out of Viagra, it is important to follow the instructions on the label. If you miss a dose, take it as soon as possible. If it is almost time for the next dose, you should wait and avoid taking the next dose at the same time. Do not take more than the recommended dose. It is important to complete the full course of treatment prescribed by your doctor, even if you feel better if you take Viagra. It is recommended to keep taking it for as long as your doctor has prescribed it. Sometimes, Viagra may take longer to work if you take it shortly before sexual activity. Viagra should not be taken with nitrates (medicines used to treat chest pain or angina) such as GTN spray or Nitroglycerin nitrates (minwayne's combination products) such as Mounjaro (MONTROSE) or Rioprim (RABP) such as Dutasteride (VITAMIL) or Vigor marketing materials such as on the label. Viagra is also used to treat high blood pressure. It may be used alone or in combination with other medications to treat erectile dysfunction. Viagra is also used to treat pulmonary hypertension. Viagra is not approved for use in women. Viagra may also be used for purposes not listed in this medication guide.

How should Viagra be taken?

The usual starting dose of Viagra is 50 mg taken with water about 1 hour before intercourse. The dosage may be increased to a maximum of 100 mg or decreased to 5 mg. The maximum recommended dose is 100 mg. It is important to take Viagra as directed by your doctor. Take Viagra at least 1 hour before or 2 hours after meals, as directed by your doctor. Do not take Viagra more than once a day. It is important to complete the full course of treatment prescribed by your doctor. Viagra may be taken with or without food, but it is important to take it at the same time each day. Viagra is usually taken about 1 hour before intercourse. Viagra is usually taken about 1 hour before sexual activity. The dosage may be increased to a maximum of 100 mg. Viagra should be taken with food.

How long does it take for Viagra to work?

The time it takes for Viagra to work varies from person to person. It is important to take Viagra at the same time each day. Viagra is usually taken as needed before intercourse. Viagra should be taken about 1 hour before or 2 hours after a meal. Viagra is usually taken about 1 hour before or 2 hours after a meal, as directed by your doctor.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Safety & Precautions

Men with heart problems, ACE-2 inhibitors, beta-blockers, antifungal drugs, acne treatments, hormonal treatments, or prostate health may be advised to avoid the use of Sildenafil.

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

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  • Alterations can occur through drug interactions, affecting the medications work or posing alarming side effects.
  • This list does not include all medications. Always consult your doctor for comprehensive information regarding any medications you may be taking.
  • Certain products can interact with Sildenafil, including the alpha-blocker sildenafil. However, Sildenafil's effectiveness is oftenLLOWUDE.
  • A dangerous drop in blood pressure arises when Sildenafil is used with nitrates. This severe drop can lead to dizziness or fainting, which can be a serious health condition.
  • Avoid use with Sildenafil nitrates, as they can lead to sudden dizziness or fainting.
  • If you're also taking an alpha-blocker for an enlarged prostate (like doxazosin or tamsulosin), it causes dangerous drops in blood pressure, leading to dizziness or fainting.
  • Drug interactions can increase the risk of adverse effects, such as chest pain, but always consult your doctor.
  • Drug interactions can lead to serious health problems if used with illegal drugs.
  • If you are pregnant, planning to become pregnant, or breastfeeding, consult with your doctor before using Sildenafil.